The Carrier-HDM includes the HDM labware immobilizing module pre-integrated into a customizable carrier. The compact design of the HDM maximizes potential carrier capacity while still providing robust labware immobilization. The novel immobilization mechanism provides fail proof performance ensuring labware does not move during piercing, aspirating, and/or dispensing. The slide and lock fingers are easily manipulated by automated grippers and are self-contained within the module resulting in a very compact footprint. Also see the HDM-cPAC and HDM for alternative configurations.